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Risk of Autism due to Hyperinsulinemia

When the genetic and biochemical abnormalities of autism are studied, symptoms of developing diabetes were found. It seems like both diabetes and autism has a same mechanism i.e. impairment of glucose tolerance and hyperinsullinemia.


Hyperinsulinemia is a condition when the body has an excessive amount of glucose in the blood stream. Insulin is further associated with obesity and type 2 diabetes. One method of testing this in autistic children is being putting them on low carbohydrate diet that minimizes their insulin secretion and then analyzing whether their could improve or not. It is suggested by Stern and he further concluded that glucose tolerance level must be seriously addressed in pregnant women as well.
Research was conducted at Rice's BioScience Research Collaborative, which is still carrying out the tests to find out the linkage of autism with diabetes. Genetic disorders like neurofibromatosis, is a disorder in which patients are most likely to suffer from autism or its related disorder Asperger’s Syndrome.


Asperger and Autism has poorly understood genetic grounds. According to the statistics of U.S. Centers for Disease Control and Prevention, every nine out of 1000 children are diagnosed with Asperger’s syndrome. There are four genes that are associated with producing proteins, which play a significant role in biochemical pathways P13/T. Their relationship with the insulin is also under consideration.
Increase in autism and diabetes seems to have a general cause that is increase in hyperinsulinemia. He found that gestational diabetes is the most important risk factor for autism. The cognitive role of insulin is widely accepted now. The nasal application of insulin has shown positive results for both Alzheimer and schizophrenic patients.


Diet low in carbohydrates is a therapeutic treatment for those having ASD and autism. Insulin should be taken seriously as it is a causative factor of autism. This needs to be further researched out so that physicians suggest the best treatment to their patients. If the risk factors are identified, the diagnosis of the disease becomes easy. Genetic or environmental factors, this area needs further investigation. Diabetes is a dangerous disease as itself is a cause of other illness as well.